Academic Background

Postdoctoral Research Scientist, NEC Laboratories, America 09/02–07/04

Postdoctoral Researcher, Department of Physics, University of California at Davis 04/00-08/02

Ph.D. The Ohio State University, Physics, March 2000

M.S. Indian Institute of Technology (IIT) Kanpur, India, Physics, May 1993

Research Interests

1. Using computational modeling and bioinformatics to study biological networks, in particular bacterial quorum-sensing networks.
    
2. Studying transcriptional regulation using comparative genomics and computational modeling, focussing on regulation of and by small RNAs in bacteria.
    
3. Using specific examples (e.g. the Min-protein system) to study how underlying physical processes, such as diffusion and membrane attachment, determine subcellular localization of proteins.
    
4. Modeling the processes (e.g. aggregation of misfolded proteins) involved in prion disease incubation.
    
5. Developing a theoretical framework for analyzing structural properties of complex networks and applying this framework to the study of networks in biology.
    

Selected Publications

1. R. V. Kulkarni and P. R. Kulkarni, "Computational approaches for the discovery of bacterial small RNAs" Methods 43 131 (2007)
    
2. P. R. Kulkarni, X. Cui, J. H. Williams, A. M. Stevens, R. V. Kulkarni, "Prediction of CsrA-regulating small RNAs in bacteria and their experimental verification in Vibrio fischeri" Nucleic Acids Res 34 3361 (2006)
    
3. R. V. Kulkarni, K. C. Huang, M. Kloster and N. S. Wingreen, "Pattern Formation within Escherichia coli: Diffusion, Membrane Attachment, and Self-Interaction of MinD Molecules" Phys. Rev. Lett 93 228103 (2004)
    
4. D. Lenz, K. Mok, B. Lilley, R. V. Kulkarni, N. Wingreen and B. Bassler, “The small RNA haperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae” Cell 118 69 (2004)
    
5. M. Chandran and R. V. Kulkarni, "Fractionalization of a flux quantum in a one-dimensional parallel Josephson junction array with alternating π-bonds" Phys. Rev. B 68 104505 (2003)
    
6. R. V. Kulkarni, A. Slepoy, R. R. P. Singh, D. L. Cox and F. Pazmandi "Theoretical
   modeling of prion disease incubation" Biophys. J. 85 707-718 (2003)
    
7. E. Almaas, R. V. Kulkarni and D. Stroud, "Characterizing the structure of small- world networks" Phys. Rev. Lett. 88 098101 (2002)